Anticoagulant Macromolecules

Anticoagulant macromolecules have gained widespread use in the clinical treatment of cardiovascular diseases, blood-contacting or implantable materials, and medical devices due to their excellent anticoagulant properties. Inspired by molecular characteristics physiological anticoagulants that play a vital role normal human coagulation anticoagulation mechanisms, diverse with special structures functional groups been developed, where they can be systematically applied biomedical field. In this Perspective, history recent progress synthetic methods for obtained purification natural products, semisynthetic methods, are discussed from aspect design. The critical application immense development potential these field biomedicine is proposed.